Evaluation of endocrine pancreas development, beta cell mass expansion, and regeneration in glis3 mutant zebrafish
The endocrine pancreas is responsible for the production of several hormones, including insulin, important in the regulation of carbohydrate metabolism and glucose homeostasis. Both the development of the endocrine pancreas and its proper function within the context of the mature organ rely on networks of transcription factors that are not yet well understood. Among these, […]
Center for the Biologic Basis of Oral/Systemic Diseases
Systemic Diseases (CBBO/SD)” is to continue the sustainability of a nationally competitive transdisciplinary research center focusing on oral healt sciences and systemic diseases within the University of Kentucky. This proposal builds upon the Phase l/ll funding for developing the research infrastructure in the College of Dentistry and supporting junior investigators to develop competitive research programs […]
Surveillance and identification of variants of concern within circulating SARS-CoV-2 across Kentucky
The emergence and circulation of SARS-CoV-2, the virus that causes COVID-19 disease, has led to >125 million infections and more than 2.5 million deaths worldwide in just over 1 year. Global sequencing efforts have identified several viral variants of concern (VOC) and interest (VOI) that result in increased transmission rates and/or increased mortality for those […]