Rhode Island Hospital Injury Control Center for Biomedical Research Excellence (COBRE)
PROJECT SUMMARY (Overall) Injury is the leading cause of death for individuals 1-44 years of age and contributes to over 30 million emergency department visits annually1. There is a tremendous need for greater scientific understanding and strategies to combat the injury epidemic yet injury control research is underfunded compared to other leading causes of […]
Injury Control COBRE
Injury occurrence is typically thought of as “bad luck” or fatalistic; however, over the last fifty years the field of injury control science has grown to demonstrate that injuries can be controlled. Many injuries can be prevented through behavioral interventions, engineering strategies, dissemination of education, and policy implementation. Mission: The Rhode Island Hospital (RIH) Injury […]
COBRE for Stress, Trauma and Resilience (STAR)
The Initiative on Stress, Trauma, and Resilience (STAR) was formed in 2019 with support from the Department of Psychiatry and Human Behavior. The STAR Initiative aims to foster transdisciplinary collaborations within Brown University, to provide training opportunities for researchers and clinicians who want to address stress and trauma, to enhance partnerships with local and community stakeholders, and to affect policy […]
COBRE: Stem Cells and Aging
This Phase II COBRE application entitled ‘Stem Cells and Aging’ focuses on neural and hematopoietic stem cells, their microenvironments and the impact of aging, fibrosis, and senescence on their regulation and evolution to diseases of the central nervous system and bone marrow. The COBRE continues to be led by Dr. Peter Quesenberry, but now adds […]
COBRE Center for Sleep and Circadian Rhythms in Child and Adolescent Mental Health
This COBRE will establish a Center on Sleep and Circadian Rhythms in Child and Adolescent Mental Health at the EP Bradley Hospital in Rhode Island. Bradley Hospital is unique in the US as a psychiatric institution exclusively focused on children and a national resource for research in child and adolescent psychiatry. Links between mental illness […]
RI- Advance Clinical and Translational Research (CTR)
The universities, hospitals, government agencies and community organizations in Rhode Island are well positioned to bridge the gaps between the worlds of clinical and basic science. Rhode Island’s small size, population demographics, and organizational structure are assets and present opportunities to implement and test transformative clinical and translational research. The health care delivery environment within […]
Rhode Island IDeA Network of Biomedical Research Excellence
The overarching goal of Rhode Island-IDeA Network of Biomedical Research Excellence (RI-INBRE) is to improve institutional capacity for biomedical research excellence and to expand student experiential training opportunities in the State of Rhode Island. We will accomplish this goal by growing statewide institutional research capacity, supporting early career research faculty development, and by providing structured […]
COBRE Center on Opioids and Overdose
We propose to build and sustain the Center of Biomedical Research Excellence (COBRE) on Opioids and Overdose at Rhode Island Hospital and affiliated research institutions. The motivation for this effort lies in the tremendous need for greater scientific understanding of the mechanisms underpinning vulnerability to opioid use disorder and a need for more effective interventions […]
COBRE for Skeletal Health & Repair
The long-term goal of the Center of Biomedical Research Excellence (COBRE) for Skeletal Health and Repair is to develop a multi-disciplinary translational research center focusing on discovering mechanisms of cartilage joint diseases and developing prevention and treatment strategies. Since the start of the COBRE eight years ago, seven full project investigators have received R01 or […]
COBRE Center for Antimicrobial Resistance and Therapeutic Discovery
Overall Resistance to antimicrobial therapies is a national and international crisis that threatens clinical practice from fundamental primary care to the most advanced medical interventions such as cancer chemotherapy and organ transplantation. Much of what we take for granted in clinical medicine could become too risky as microorganisms have become increasingly resistant to our newest […]