Research Expanding Access to Child Health (REACH)
Abstract Text PROJECT SUMMARY The overall goal of this Center of Biomedical Research Excellence (COBRE) is to strengthen pediatric health care research infrastructure in Delaware, specifically that at the Alfred I. duPont Hospital for Children. Consistent with this goal, we will establish a thematic, multidisciplinary health research system – The REACH (Research Expanding Access to […]
Increasing IDeA state Biomedical Entrepreneurship via Ecosystem, Enterprises & Experts
The proposed DE iRED program consists of university and private sector partnerships to deliver a comprehensive program that will engage and support biomedical innovators in the early stages of technology commercialization by addressing key bottlenecks in the startup process as identified both in the solicitation and by the DRIVEN Accelerator Hub. According to DRIVEN’s Voice […]
Discovery of Chemical Probes and Therapeutic Leads
In this COBRE, novel approaches to developing chemical probes and therapeutic leads will be pursued by a diverse team of scientists. This COBRE will create new libraries for high-throughput screening, provide new perspectives on innate immune response and neurodegenerative disease, enable new screening technology, and advance the state of the art in virtual screening. The […]
Delaware Clinical and Translational Research ACCEL Program
Administrative The DE-CTR ACCEL Program (ACCEL), was launched in September of 2013 and brought together four institutions with complementary missions to dramatically strengthen the clinical and translational research capabilities within and across all of our partner institutions. These institutions are: the University of Delaware (lead institution) (UD), Christiana Care Health System (CCHS), and Nemours/ Alfred […]
The Delaware Comprehensive Sickle Cell Research Center
The Delaware Comprehensive Sickle Cell Research Program (a consortium between A.I. DuPont Hospital for Children and Delaware State Univ.) will build upon strengths in Biomedical Research, clinical care and recent recruitments to create a sustainable infrastructure supportive of target investigators and state-of-the art research. Three Target Investigator proposals and two Pilots comprise a well balanced […]
Delaware Center for Musculoskeletal Research
The musculoskeletal system has both mechanical and biological functions—it generates, transmits, and supports forces, and it regulates organ-level homeostasis and whole-body metabolism. The mechanics and biology of the musculoskeletal system are inextricably intertwined and long-ranging, where mechanical cues, molecular signals, and cell interactions affect each other across multiple scales, from the body, to organ, tissue, […]
Renewal of Delaware Center for Neuroscience Research
The Delaware Center for Neuroscience Research, established in 2012 with a phase I COBRE award, is a collaboration between Delaware State University (DSU) and the University of Delaware (UD) that uniquely brings together faculty and research resources from two very different institutions: a minority-serving, undergraduate university with an emerging strength in neuroscience research (DSU), and […]
Center of Biomedical Research Excellence in Cardiovascular Health
Cardiovascular diseases (CVD) such as heart disease, heart failure, and stroke remain the number one cause of death in the U.S. for both men and women. CVD affect Delawareans at a rate significantly above the national average. According to the Centers for Disease Control, Delaware is not even in the top half (i.e., better half) […]
Center for Pediatric Research
The overall objective of this proposal is to build on the success of COBRE phase I and II grants, as well as 3 ARRA supplements. Thus, the goal of Phase III is to sustain infrastructure cores, mentorship programs, and pilot project programs, in order to provide the Center for Pediatric Research (CPR) the resources to […]
Molecular Design of Advanced Biomaterials
We propose to build on the success of COBRE phase I and phase II awards to establish four research cores that will provide the infrastructure to take our Center to the next level. In addition, COBRE III will provide a mechanism for pilot research projects to continue to develop vibrant teams of investigators in biomaterials […]