New Mexico IDeA Networks of Biomedical Research Excellence
This project is a continuation of the New Mexico Idea Network of Biomedical Research Excellence (NM- INBRE), a statewide network that promotes biomedical and community-based research and training through scientific research in the following thematic areas: structure and function of biomolecules, cell and organism, pathogens, and population and community health. The network includes nine institutions […]
Deep sequencing SARS-CoV-2 samples from New Mexico to interrogate immunological selection on genetic variants
Although vaccination has blunted the impact of the SARS-CoV-2 pandemic in several countries, the future impact of this virus will depend on its transmissibility, virulence, and ability to evade naturally-acquired and vaccine- mediated immunity. All three phenotypes are currently in flux due to the evolution and spread of novel SARS- CoV-2 variants of concern. Importantly, […]
Circulating Lipid and miRNA Narkers for Early Detection of Breast Cancer Among Women with Abnormal Mammograms
Breast cancer is the most common cancer among women in the world. When breast cancer is found in early stages, it can be effectively treated or even cured, but treating a patient in later stages is very difficult. Thus, early detection of breast cancer is critical. Mammography is the current gold standard for breast cancer […]
Hawaii Statewide Research and Education Partnership
The Hawaii Statewide Research and Education Partnership (HiSREP) comprises a network of nearly all of the institutions of higher learning in the state of Hawaii, specifically 4 primarily undergraduate institutions (PUIs), 1 University of Hawaii (UH) college and 4 UH community colleges under the management of the lead R1 institution, the University of Hawaii at […]
Surveillance of SARS-CoV-2 Variants in Hawaii
The Hawaii Statewide Research and Education Partnership (HiSREP) comprises a network of nearly all of the institutions of higher learning in the state of Hawaii, specifically 4 primarily undergraduate institutions (PUIs), 1 University of Hawaii (UH) college and 4 UH community colleges under the management of the lead R1 institution, the University of Hawaii at […]
Mammalian Hibernation Research- A Path Towards a Center for Transformative Research in Metabolism
Overall This application is in response to PAR-16-415, Centers of Biomedical Research Excellence (COBRE) (P20). The proposed phase 1 center (P1C) is built on a strong foundation and long-term commitment to hibernation research at the University of Alaska’s Institute of Arctic Biology (IAB). The objective of the P1C is to use the expertise at IAB, […]
Integrative Center for Environmental Microbiomes and Human Health
The goal of the proposed COBRE program is to create an Integrative Center for Environmental Microbiomes and Human Health (ICEMHH) in response to the 2016 announcement of the National Microbiome Initiative (NMI). The NMI was conceived through the recognition that humans are both connected to and reliant upon the microbial communities that constitute the Earth’s […]
COBRE-DIABETES
Overall The John A. Burns School of Medicine (JABSOM) at the University of Hawaii (UH) proposes to develop a multidisciplinary Hawaii-based Center of Biomedical Research Excellence (COBRE) in Diabetes Mellitus (DM). This Center will initially span departmental and eventually campus borders to promote the metabolic health of the people of Hawaii and the Pacific region. […]
Center for Translational Research on Aging
Kuakini Medical Center (Kuakini) proposes to develop a multidisciplinary Hawai’i-based Center of Biomedical Research Excellence (COBRE) for translational research on aging. This Center will draw on the most promising junior investigators from across the state with cross-institutional and interdisciplinary collaborative efforts between Kuakini, the University of Hawaii John A. Burns School of Medicine (JABSOM), and […]
IBR-COBRE Phase III
Overall Component Approximately 70,000 babies born in the U.S. in 2015 were conceived by artificial reproductive technologies (ART), which involves one of two techniques: in vitro fertilization (IVF) in which the sperm fertilizes the egg in vitro, or intracytoplasmic sperm injection (ICSI) in which the sperm is injected into the egg using micromanipulation. The rapid […]