Igor Roninson, Ph.D.  Professor, Director, Center for Targeted Therapeutics Department: Drug Discovery & Biomedical Sciences (DDBS), College of Pharmacy.

Research Interests:

The main research topic of our laboratory is the role of the CDK8/19 kinase in transcriptional reprogramming in the context of cancer, aging-associated diseases, and inflammatory and viral diseases. CDK8 and CDK19 are closely related members of the cyclin-dependent kinase (CDK) family that, unlike some other CDKs, do not regulate cell cycle progression. Instead, CDK8 and CDK19 are alternative components of the regulatory module of the transcriptional Mediator complex, where they interact with their regulatory subunit Cyclin C and the proteins MED12 and MED13.

He is also working as Principal Investigator of Center for Targeted Therapeutics, South Carolina.

Igor Roninson – College of Pharmacy | University of South Carolina (sc.edu)