Dr. Lawrence Cornett is Professor and Director, Arkansas INBRE, Ph.D., University of California, Davis. National Committee Member NAIPI

His research interests are focused primarily on the homeostatic roles of the neurohypophysial hormone vasotocin in the domestic chicken and secondarily on the regulation of adrenergic receptor gene expression in mammals. Regarding the actions of vasotocin, immunohistochemical techniques, radioimmunoassays, and in situ hybridization histochemistry are used to investigate the regulation of vasotocin gene expression in the chicken hypothalamus under conditions of osmotic stress and during oviposition.

His laboratory has cloned and pharmacologically characterized receptors that bind vasotocin and transduce its physiological effects in the shell gland and the anterior pituitary gland.  Regarding adrenergic receptors, my laboratory has studied the mechanisms of glucocorticoid regulation of beta2-adrenergic receptor gene expression in liver and airway smooth muscle cells.

In addition, Dr. Cornett is the Director of the Arkansas IDeA Network of Biomedical Research Excellence (Arkansas INBRE) (https://inbre.uams.edu/). The Arkansas INBRE is funded by a grant from the National Institute of General Medical Sciences under the Institutional Development Award IDeA Program.

The goal of the Arkansas INBRE is to expand and strengthen the infrastructure for biomedical research of academic institutions in the state by supporting a multidisciplinary research network united by the scientific theme of Cellular Signaling, Growth, and Differentiation. Lawrence Cornett, Ph.D. | UAMS College of Medicine