Scott Earley Ph.D.: Contact, Professor of Pharmacology, Cellular and Molecular Pharmacology & Physiology | Department of Pharmacology

Research

My lab is focused on elucidating the functional significance of the transient receptor potential (TRP) superfamily of cation channels in the cerebral vasculature and other organ systems. The mammalian TRP superfamily is composed of 28 distinct gene products assigned to six subfamilies based on sequence homology.

TRP channels act as fundamental sensors of the environment at the cellular level and mediate appropriate responses to stimuli such as light, pressure, temperature, changes in osmolarity, and certain chemical agonists. Although prominent in sensory neurons, multiple TRP channels are present in most types of cells.

We are primarily interested in learning how TRP channels are involved in smooth muscle excitability and contractility, endothelium-dependent vasodilation, and cellular proliferation during pathophysiological conditions.

He is also working Principal Investigator of Nevada Center of Biomedical Research Excellence in Molecular and Cellular Transduction in the Cardiovascular System, Nevada

Scott Earley: Contact: Directory: University of Nevada, Reno School of Medicine (unr.edu)