Lesly Temesvary, Alumni Distinguished Professor

Education:
Ph.D., Biology, University of Windsor, 1993
B.Sc., Microbiology and Immunology, McGill University, 1987

The overall goal of the research in Dr. Temesvari’s laboratory is to understand the pathogenesis of the human protozoan parasite, Entamoeba histolytica. This is the causative agent of amoebic dysentery and amoebic liver abscess; up to 50,000,000 people worldwide are infected annually. Secretion, phagocytosis, and parasite-host interactions are important virulence functions of E. histolytica. Thus, using state-of-art molecular, biochemical, genetic, and cellular techniques, the Temesvari laboratory seeks to understand the virulence functions by studying (i) four Rab GTPases (master regulators of vesicle trafficking), (ii) several components of the PI 3-kinase signaling pathway, and (iii) lipid rafts. The insight gained through these studies may lead to the rational design of novel anti-Entamoeba agents.

She is also working as Principal Investigator of COBRE: Eukaryotic Pathogens Innovation Center (EPIC), South Carolina.

Lesly Temesvari | Clemson University, South Carolina

https://naipi.org/2021/06/26/cobreeukaryotic-pathogens-innovation-center/